Article
Association and causality between diabetes and activin A: a two-sample Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2024
Wang Mengqiao
Abstract excerpt
Activin A, a cytokine belonging to the transforming growth factor-beta (TGF-β) superfamily, mediates a multifunctional signaling pathway that is essential for embryonic development, cell differentiation, metabolic regulation, and physiological equilibrium. Biomedical research using diabetes-based model organisms and cellular cultures reports evidence of different activin A levels between diabetic and control...
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