Article
CXCL12 Gene Polymorphisms and Serum Levels: Associations with Multiple Sclerosis Prevalence and Clinical Parameters in Lithuania.
International journal of molecular sciences - 3 Sept 2024
Valiukevicius Paulius, Kaikaryte Kriste, Gedvilaite-Vaicechauskiene Greta, Balnyte Renata, Liutkeviciene Rasa
Abstract excerpt
Our study aimed to investigate the associations between CXCL12 rs1029153, rs1801157, and rs2297630 single-nucleotide polymorphisms (SNPs), CXCL12 protein levels, MS prevalence, and clinical parameters. This study included 250 individuals diagnosed with MS and 250 sex- and age-matched healthy control individuals from Lithuania. The SNPs were genotyped with real-time PCR-based assays. The CXCL12 protein...
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