Article
Quasispecies of SARS-CoV-2 revealed by single nucleotide polymorphisms (SNPs) analysis.
Virulence - 1 Dec 2021
Gao Rongsui, Zu Wenhong, Liu Yang, Li Junhua, Li Zeyao, Wen Yanling, Wang Haiyan, Yuan Jing, Cheng Lin, Zhang Shengyuan, Zhang Yu, Zhang Shuye, Liu Weilong, Lan Xun, Liu Lei, Li Feng, Zhang Zheng
Abstract excerpt
New SARS-CoV-2 mutants have been continuously indentified with enhanced transmission ever since its outbreak in early 2020. As an RNA virus, SARS-CoV-2 has a high mutation rate due to the low fidelity of RNA polymerase. To study the single nucleotide polymorphisms (SNPs) dynamics of SARS-CoV-2, 158 SNPs with high confidence were identified by deep meta-transcriptomic sequencing, and the most common SNP type was C...
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