Article
Analysis of 3.5 million SARS-CoV-2 sequences reveals unique mutational trends with consistent nucleotide and codon frequencies.
Virology journal - 17 Feb 2023
Fumagalli Sarah E, Padhiar Nigam H, Meyer Douglas, Katneni Upendra, Bar Haim, DiCuccio Michael, Komar Anton A, Kimchi-Sarfaty Chava
Abstract excerpt
BACKGROUND: Since the onset of the SARS-CoV-2 pandemic, bioinformatic analyses have been performed to understand the nucleotide and synonymous codon usage features and mutational patterns of the virus. However, comparatively few have attempted to perform such analyses on a considerably large cohort of viral genomes while organizing the plethora of available sequence data for a month-by-month analysis to observe...
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