Article
Concurrent detection of the mitochondrial DNA copy number and the +35G/C polymorphism in the mitochondrial transcription factor A gene in endometriosis.
Archives of biochemistry and biophysics - 1 Nov 2024
El Derbaly Sara A, Mohamed Ola A, Ghanaym Naglaa M, Azmy Rania, Abdelgayed Alaa M, Abbas Mona A
Abstract excerpt
BACKGROUND AND AIM: Endometriosis is a chronic gynecological inflammatory disease. The mitochondrial DNA copy number (mtDNA CN) and mitochondrial transcription factor A (TFAM) are known to contribute to human pathologies and cancer. Therefore, this study aims to reveal the association of mtDNA CN and TFAM+35G/C (rs1937) polymorphism with the risk of endometriosis in Egyptian females. MATERIALS AND METHODS: This...
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