Article
Polymorphisms of mitochondrial DNA control region are associated to endometriosis.
Journal of assisted reproduction and genetics - 1 Mar 2018
Andres Marina Paula, Cardena Mari Maki Siria Godoy, Fridman Cintia, Podgaec Sergio
Abstract excerpt
PURPOSE: Polymorphisms in the control region of mitochondrial DNA (mtDNA) can affect generation of reactive oxygen species and impact in the pathogenesis of endometriosis. This study investigated the association of mtDNA polymorphisms with endometriosis. METHODS: Patients were divided in two groups: endometriosis (n = 90) and control (n = 92). Inclusion criteria were as follows: women between 18 and 50 years,...
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