Article
Transcriptomic profiles of myxofibrosarcoma and undifferentiated pleomorphic sarcoma correlate with clinical and genomic features.
The Journal of pathology - 1 Nov 2024
Mitra Shamik, Farswan Akanksha, Piccinelli Paul, Sydow Saskia, Hesla Asle, Tsagkozis Panagiotis, Vult von Steyern Fredrik, Almqvist Martin, Eriksson Mikael, Magnusson Linda, Nilsson Jenny, Pillay Nischalan, Mertens Fredrik
Abstract excerpt
Myxofibrosarcoma (MFS) and undifferentiated pleomorphic sarcoma (UPS) are two common and aggressive subtypes of soft tissue sarcoma. The aim of this study was to assess potential transcriptomic differences between MFS and UPS tumours and to evaluate the extent to which differences in gene expression profiles were associated with genomic and clinical features. The study included 162 patients with tumours diagnosed...
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