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Article

Testing the causal relationship of fat and sugar intake with depression and cortisol: a Mendelian Randomisation study.

Translational psychiatry - 10 Sept 2024

Buczkowska Matylda, Iob Eleonora

Abstract excerpt

Unhealthy diets high in fat and sugar content may have an impact on psychological health and increase the risk of Major Depressive Disorder (MDD) and stress levels. On the other hand, MDD and stress might be related to food choices and intake. However, it is not clear whether diet, and specifically fat and sugar intake, is causally related to stress and MDD, and whether this relationship may be bi-directional....

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Depressive Disorder, Major
Dietary Fats
Genome-Wide Association Study
Hydrocortisone
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Stress, Psychological

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Identifiers

PMID: 39256365
DOI: 10.1038/s41398-024-03089-2
PMCID: PMC11387734

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