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Article

Causal effects of sepsis on structural changes in cerebral cortex: A Mendelian randomization investigation.

Medicine - 6 Sept 2024

Zhou Dengfeng, Wang Weina, Gu Jiaying, Lu Qiaofa

Abstract excerpt

Previous research has shown a strong correlation between sepsis and brain structure. However, whether this relationship represents a causality remains elusive. In this study, we employed Mendelian randomization (MR) to probe the associations of genetically predicted sepsis and sepsis-related death with structural changes in specific brain regions. Genome-wide association study (GWAS) data for sepsis phenotypes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39252275
DOI: 10.1097/MD.0000000000039404
PMCID: PMC11383497

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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