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Article

Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols.

Journal of natural products - 24 Mar 2017

Crüsemann Max, O'Neill Ellis C, Larson Charles B, Melnik Alexey V, Floros Dimitrios J, da Silva Ricardo R, Jensen Paul R, Dorrestein Pieter C, Moore Bradley S

Abstract excerpt

In order to expedite the rapid and efficient discovery and isolation of novel specialized metabolites, while minimizing the waste of resources on rediscovery of known compounds, it is crucial to develop efficient approaches for strain prioritization, rapid dereplication, and the assessment of favored cultivation and extraction conditions. Herein we interrogated bacterial strains by systematically evaluating...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28335604
DOI: 10.1021/acs.jnatprod.6b00722
PMCID: PMC5367486

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