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Novel bioactive natural products from bacteria via bioprospecting, genome mining and metabolic engineering

4 Mar 2019

Abstract excerpt

For over seven decades, bacteria served as a valuable source of bioactive natural products some of which were eventually developed into drugs to treat infections, cancer and immune system-related diseases. Traditionally, novel compounds produced by bacteria were discovered via conventional bioprospecting based on isolation of potential producers and screening their extracts in a variety of bioassays. Over time,...

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PMID: 30834674
DOI: 10.1111/1751-7915.13398

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