Article
Characterising the role of enolase in a stable Small Colony Variant of Staphylococcus aureus isolated from a diabetic foot infection patient with osteomyelitis.
Microbial pathogenesis - 1 Nov 2024
Lee James, Carda-Diéguez Miguel, Vreugde Sarah, Cooksley Clare, Mashayamombe Matipaishe, Dawson Joseph, Fitridge Robert, Mira Alex, Zilm Peter S, Kidd Stephen P
Abstract excerpt
The switch to alternate cell types by Staphylococcus aureus creates sub-populations even within an active population, that are highly resilient, tolerant to antibiotics and lack clinical symptoms of infection. These cells present a challenge for clinical treatment where even after initial intervention has seemingly cleared the infection, these alternate cell types persist within tissue to revert and cause...
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