Article
Distribution of MR-induced sex-linked recessive lethal mutations in Drosophila melanogaster.
Mutation research - 1 Jan 2000
Eeken J C, Sobels F H, Hyland V, Schalet A P
Abstract excerpt
In the 'doubling-dose' method currently used in genetic risk evaluation, two principle assumptions are made and these are: (1) there is proportionality between spontaneous and induced mutations and (2) the lesions that lead to spontaneous and induced mutations are essentially similar. The studies...
Topics
- Animals
- Chromosome Mapping
- DNA Repair
- Drosophila melanogaster
- Female
- Genes, Lethal
- Genes, Recessive
- Genetic Linkage
- Mutation
- X Chromosome
- X-Rays