Article
Accuracy and technical characteristics of CYP2C19 point of care tests: a systematic review.
Pharmacogenomics - 1 Jan 2024
Tomlinson Eve, Cooper Chris, Jones Hayley E, Manzano Catalina Lopez, Palmer Rachel, Carroll Joe, Sadek Ayman, Welton Nicky J, Leeflang Mariska, Whiting Penny
Abstract excerpt
Aim: To assess the accuracy and technical characteristics of CYP2C19 point of care tests (POCTs).Patients & methods: Systematic review of primary studies, in any population or setting, that evaluated POCTs for detecting CYP2C19 loss of function (LOF) alleles.Results: Eleven studies provided accuracy data (eight Spartan; one Genomadix Cube; one GMEX; one Genedrive). The POCTs had very high sensitivity and...
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