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Article

Identification and validation of CCL2 as a potential biomarker relevant to mast cell infiltration in the testicular immune microenvironment of spermatogenic dysfunction

23 May 2023

Abstract excerpt

BACKGROUND: Spermatogenic dysfunction is an important cause of azoospermia. Numerous studies have focused on germ-cell-related genes that lead to spermatogenic impairment. However, based on the immune-privileged characteristics of the testis, the relationship of immune genes, immune cells or immune microenvironment with spermatogenic dysfunction has rarely been reported. RESULTS: Using integrated methods...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37221631
DOI: 10.1186/s13578-023-01034-2

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