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Article

Noncanonical inheritance of phenotypic information by protein amyloids.

Nature cell biology - 1 Oct 2024

Eroglu Matthew, Zocher Tanner, McAuley Jacob, Webster Rachel, Xiao Maggie Z X, Yu Bin, Mok Calvin, Derry W Brent

Abstract excerpt

All known heritable phenotypic information in animals is transmitted by direct inheritance of nucleic acids, their covalent modifications or histone modifications that modulate expression of associated genomic regions. Nonetheless, numerous familial traits and disorders cannot be attributed to known heritable molecular factors. Here we identify amyloid-like protein structures that are stably inherited in...

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Identifiers

PMID: 39223373
DOI: 10.1038/s41556-024-01494-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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