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Article

The contribution of white matter changes to clinical phenotype in progressive supranuclear palsy.

Journal of neurology - 1 Oct 2024

Tepedino Maria Francesca, Diana Francesco, Abate Filomena, Avallone Anna Rosa, Caterino Miriam, Erro Roberto, Pellecchia Maria Teresa, Manara Renzo, Barone Paolo, Picillo Marina

Abstract excerpt

White matter hyperintensities (WMH) are considered magnetic brain imaging (MRI) biomarkers of cerebral small vessel disease but their clinical role in neurodegenerative-related disorders is poorly understood. This study describes the distribution of WMH on brain MRI in Progressive Supranuclear Palsy (PSP) in comparison with Parkinson's disease (PD) and explores their possible impact on disease's features. Sixty...

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Identifiers

PMID: 39222284
DOI: 10.1007/s00415-024-12662-0
PMCID: PMC11447107

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