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Microbiota transfer early after birth modulates genetic susceptibility to chronic arthritis in mice.

Microbes and infection - 1 Feb 2025

Borrego Andrea, Koury Cabrera Wafa Hanna, Souza Alanis Tiozzo, Eto Silas Fernandes, de Oliveira Silvio Luis, Rodrigues Josias, Jensen José Ricardo

Abstract excerpt

Genetics is central to the susceptibility or resistance to autoimmunity, and mounting evidence indicates that the intestinal microbiota also plays an essential role. In murine arthritis models, short-chain fat acid supplementation reduces disease severity by modulating tryptophan-metabolizing bacteria. Common microbiota transfer methods modulate arthritis severity, however, they are not practical for chronic...

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PMID: 39216617
DOI: 10.1016/j.micinf.2024.105411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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