Increased somatic mosaicism in autosomal and X chromosomes for suicide death.

Abstract excerpt

Mosaic chromosomal alterations (mCAs) are classified as mosaic deletions (loss), copy-neutral loss of heterozygosity (CN-LOH), and duplications (gain), attracting special attention as biological aging-related acquired genetic alterations. While these mCAs have been linked with aging and various diseases, no study has investigated their association with suicide risk which is associated with abnormal biological...

Topics

• Humans
• Mosaicism
• Female
• Male
• Chromosomes, Human, X
• Polymorphism, Single Nucleotide