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VP3 protein of Senecavirus A promotes viral IRES-driven translation and attenuates innate immunity by specifically relocalizing hnRNPA2B1

29 Aug 2024

Abstract excerpt

ABSTRACT Viruses deploy sophisticated strategies to hijack the host’s translation machinery to favor viral protein synthesis and counteract innate cellular defenses. However, little is known about the mechanisms by which Senecavirus A (SVA) controls the host’s translation. Using a series of sophisticated molecular cell manipulation techniques, heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) was...

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Animal Disease Management and Epidemiology
Animal Virus Infections Studies
Viral Infections and Immunology Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39207136
DOI: 10.1128/jvi.01227-24

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