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Phylodynamic and Epistatic Analysis of Coxsackievirus A24 and Its Variant.

Viruses - 8 Aug 2024

Cheng Chia-Chi, Chu Pei-Huan, Huang Hui-Wen, Ke Guan-Ming, Ke Liang-Yin, Chu Pei-Yu

Abstract excerpt

Coxsackievirus A24 (CV-A24) is a human enterovirus that causes acute flaccid paralysis. However, a Coxsackievirus A24 variant (CV-A24v) is the most common cause of eye infections. The causes of these variable pathogenicity and tissue tropism remain unclear. To elucidate the phylodynamics of CV-A24 and CV-A24v, we analyzed a dataset of 66 strains using Bayesian phylodynamic approach, along with detailed sequence...

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PMID: 39205241
DOI: 10.3390/v16081267
PMCID: PMC11359322

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