Article
Global Evolution and Phylodynamics of Coxsackievirus A4.
Journal of medical virology - 1 May 2026
Han Zhenzhi, Li Jichen, Xiao Jinbo, Chen Dongmei, Jia Liping, Fu Hanhaoyu, Li Zeng, Wang Rui, Zhang Kexiang, Jiang Mingli, Xu Yanpeng, Yang Qian, Zhao Linqing, Zhang Yong
Abstract excerpt
Coxsackievirus A4 (CVA4) is an enterovirus associated with diverse clinical syndromes, yet its global evolution and transmission dynamics remain poorly defined. This study aimed to characterize the molecular epidemiology, evolutionary history, and phylodynamic patterns of CVA4 at both local and global scales. In 2024, 34 CVA4 infections were identified during a localized herpangina outbreak in Beijing, primarily...
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