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Neurosteroid Levels in GBA Mutated and Non-Mutated Parkinson's Disease: A Possible Factor Influencing Clinical Phenotype?

Biomolecules - 17 Aug 2024

Cavallieri Francesco, Lucchi Chiara, Grisanti Sara, Monfrini Edoardo, Fioravanti Valentina, Toschi Giulia, Di Rauso Giulia, Rossi Jessica, Di Fonzo Alessio, Biagini Giuseppe, Valzania Franco

Abstract excerpt

Neurosteroids are pleiotropic molecules involved in various neurodegenerative diseases with neuroinflammation. We assessed neurosteroids' serum levels in a cohort of Parkinson's Disease (PD) patients with heterozygous glucocerebrosidase (GBA) mutations (GBA-PD) compared with matched cohorts of consecutive non-mutated PD (NM-PD) patients and healthy subjects with (GBA-HC) and without (NM-HC) GBA mutations. A...

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Identifiers

PMID: 39199409
DOI: 10.3390/biom14081022
PMCID: PMC11352262

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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