Article
Genome-wide association study for metabolic syndrome reveals APOA5 single nucleotide polymorphisms with multilayered effects in Koreans.
Lipids in health and disease - 28 Aug 2024
Park Young Jun, Moon Sungji, Choi Jaeyong, Kim Juhyun, Kim Hyun-Jin, Son Ho-Young, Im Sun-Wha, Kim Jong-Il
Abstract excerpt
BACKGROUND AND PURPOSE: Genome-wide association studies (GWAS) of metabolic syndrome (MetS) have predominantly focused on non-Asian populations, with limited representation from East Asian cohorts. Moreover, previous GWAS analyses have primarily emphasized the significance of top single nucleotide polymorphisms (SNPs), poorly explaining other SNP signals in linkage disequilibrium. This study aimed to reveal the...
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