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The kinesin motor POS3 and the microtubule polymerase MOR1 coordinate chromosome congression during mitosis in Arabidopsis.

The Plant cell - 2 Apr 2025

Chen Yu, Liu Haofeng, Li Yuanfeng, Shen Xiao, Li Shuting, Yang Lan, An Xue, Lei Pei, Wang Xiaomin, Zhang Hongchang, Sheen Jen, Yu Fei, Liu Xiayan

Abstract excerpt

Faithful chromosome segregation during mitosis is crucial for eukaryotic organisms. Centromere-associated protein-E (CENP-E), a kinetochore-localized kinesin motor, facilitates chromosome congression during mitosis in animals. However, it remains unclear whether plants rely on kinesins similar to CENP-E for chromosome alignment. In our genetic screens for Arabidopsis (Arabidopsis thaliana) mutants that are...

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Identifiers

PMID: 40096489
DOI: 10.1093/plcell/koaf053
PMCID: PMC11975291

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