Article
GIGAS CELL1, a novel negative regulator of the anaphase-promoting complex/cyclosome, is required for proper mitotic progression and cell fate determination in Arabidopsis.
The Plant cell - 1 Dec 2011
Iwata Eriko, Ikeda Saki, Matsunaga Sachihiro, Kurata Mariko, Yoshioka Yasushi, Criqui Marie-Claire, Genschik Pascal, Ito Masaki
Abstract excerpt
Increased cellular ploidy is widespread during developmental processes of multicellular organisms, especially in plants. Elevated ploidy levels are typically achieved either by endoreplication or endomitosis, which are often regarded as modified cell cycles that lack an M phase either entirely or partially. We identified GIGAS CELL1 (GIG1)/OMISSION OF SECOND DIVISION1 (OSD1) and established that mutation of this...
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