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Article

Integrative multi-omics characterization of hepatocellular carcinoma in Hispanic patients.

Journal of the National Cancer Institute - 1 Dec 2024

Das Debodipta, Wang Xiaojing, Chiu Yu-Chiao, Bouamar Hakim, Sharkey Francis E, Lopera Jorge E, Lai Zhao, Weintraub Susan T, Han Xianlin, Zou Yi, Chen Hung-I H, Zeballos Torrez Carla R, Gu Xiang, Cserhati Matyas, Michalek Joel E, Halff Glenn A, Chen Yidong, Zheng Siyuan, Cigarroa Francisco G, Sun Lu-Zhe

Abstract excerpt

BACKGROUND: The incidence and mortality rates of hepatocellular carcinoma among Hispanic individuals in the United States are much higher than in non-Hispanic White people. We conducted multi-omics analyses to elucidate molecular alterations in hepatocellular carcinoma among Hispanic patients. METHODS: Paired tumor and adjacent nontumor samples were collected from 31 Hispanic hepatocellular carcinomas in South...

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Source

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Identifiers

PMID: 39189979
DOI: 10.1093/jnci/djae207
PMCID: PMC11630563

Genes

AXIN2
CTNNB1
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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