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Established and Emerging Nucleic Acid Therapies for Familial Hypercholesterolemia

26 Aug 2024

Abstract excerpt

Familial hypercholesterolemia (FH) is a genetic disease that leads to elevated low-density lipoprotein cholesterol levels and risk of coronary heart disease. Current therapeutic options for FH remain relatively limited and only partially effective in both lowering low-density lipoprotein cholesterol and modifying coronary heart disease risk. The unique characteristics of nucleic acid therapies to target the...

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PMID: 39186530
DOI: 10.1161/circulationaha.123.067957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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