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Non-invasive CT radiomic biomarkers predict microsatellite stability status in colorectal cancer: a multicenter validation study

26 Aug 2024

Abstract excerpt

BACKGROUND: Microsatellite instability (MSI) status is a strong predictor of response to immunotherapy of colorectal cancer. Radiogenomic approaches promise the ability to gain insight into the underlying tumor biology using non-invasive routine clinical images. This study investigates the association between tumor morphology and the status of MSI versus microsatellite stability (MSS), validating a novel radiomic...

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PMID: 39186200
DOI: 10.1186/s41747-024-00484-8

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