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Inference of essential genes in Brugia malayi and Onchocerca volvulus by machine learning and the implications for discovering new interventions

2 Aug 2024

Abstract excerpt

Detailed explorations of the model organisms Caenorhabditis elegans (elegant worm) and Drosophila melanogaster (vinegar fly) have substantially improved our knowledge and understanding of biological processes and pathways in metazoan organisms. Extensive functional genomic and multi-omic data sets have enabled the discovery and characterisation of ‘essential’ genes that are critical for the survival of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39185442
DOI: 10.1016/j.csbj.2024.07.025

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