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New clinicopathological concept of endometrial carcinoma with integration of histological features and molecular profiles.

Pathology international - 1 Oct 2024

Yasuda Masanori

Abstract excerpt

The dual-stratified pathway of endometrial carcinomas (ECs) has long been dominant. However, in 2013, The Cancer Genome Atlas (TCGA) defined four EC subgroups with distinctive prognoses. Inspired by TCGA, in 2018, the Proactive Molecular Risk Classifier for Endometrial Cancer (ProMisE) provided four pragmatic molecular classifiers to apply surrogate immunohistochemical markers to TCGA subgroup categorization....

Topics

Humans
Female
Endometrial Neoplasms
Biomarkers, Tumor
Adenocarcinoma
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39175262
DOI: 10.1111/pin.13471
PMCID: PMC11551833

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