Article
An approach for developing a blood-based screening panel for lung cancer based on clonal hematopoietic mutations.
PloS one - 1 Jan 2024
Anandakrishnan Ramu, Shahidi Ryan, Dai Andrew, Antony Veneeth, Zyvoloski Ian J
Abstract excerpt
Early detection can significantly reduce mortality due to lung cancer. Presented here is an approach for developing a blood-based screening panel based on clonal hematopoietic mutations. Animal model studies suggest that clonal hematopoietic mutations in tumor infiltrating immune cells can modulate cancer progression, representing potential predictive biomarkers. The goal of this study was to determine if the...
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