Article
Recent advances in the use of tyrosine kinase inhibitors against thyroid cancer.
Expert opinion on pharmacotherapy - 1 Aug 2024
Ferrari Silvia Martina, Patrizio Armando, Stoppini Giulio, Elia Giusy, Ragusa Francesca, Balestri Eugenia, Botrini Chiara, Rugani Licia, Barozzi Emilio, Mazzi Valeria, La Motta Concettina, Antonelli Alessandro, Fallahi Poupak
Abstract excerpt
INTRODUCTION: Oncogenic tyrosine kinases (TK) are enzymes that play a key role in cell growth and proliferation and their mutations can lead to uncontrolled cell growth and development of aggressive cancer. This knowledge has led to the development of new classes of drugs, Tyrosine kinase inhibitors (TKI). They target oncogenic kinases who are associated with advanced radioactive iodine (RAI) refractory TC, which...
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