Article
The interaction between obesity and RAGE polymorphisms on the risk of knee osteoarthritis in Chinese population.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2012
Han Zhu, Liu Qingpeng, Sun Chongyi, Li Ying
Abstract excerpt
BACKGROUND: The receptor for advanced glycation end products (RAGE) has been reported to relate to osteoarthritis (OA), however, the role of RAGE genetic variants in OA remains unknown. METHOD: A total of 233 patients with primary knee OA and 255 healthy volunteer were recruited. Three RAGE gene polymorphisms, namely, Gly82Ser (rs2070600). -374T/A (rs1800624) and 429T/C (rs1800625) were genotyped. RESULTS: Of all...
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