Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular pathophysiology of germline mutations in acute myeloid leukemia.

International journal of hematology - 1 Oct 2024

Nagata Yasunobu

Abstract excerpt

Germline (GL) predisposition to acute myeloid leukemia (AML) has been established as an independent disease entity in the latest World Health Organization classification. Following the American College of Medical Genetics and Genomics guidelines, GL variants were interpreted as causal if they were classified as "pathogenic." GL predisposition can be divided into three groups with different phenotypes, and play an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to DEAD-box RNA Helicases
Share to GATA2 Transcription Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Germ-Line Mutation

Share to Leukemia, Myeloid, Acute

Share to Myelodysplastic Syndromes

Source

Identifiers

PMID: 39150677
DOI: 10.1007/s12185-024-03824-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular pathophysiology of germline mutations in acute myeloid leukemia.PMID 39150677Read ↗

Germline predisposition to myeloid neoplasms: Characteristics and management of high versus variable penetrance disorders.Semantic proximity Read ↗

Inherited Predispositions to Myeloid Neoplasms: Pathogenesis and Clinical ImplicationsSemantic proximity Read ↗

[Myeloid neoplasms with germline predisposition].Semantic proximity Read ↗

Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults.Semantic proximity Read ↗

Advances in germline predisposition to acute leukaemias and myeloid neoplasms.Semantic proximity Read ↗

Prevalence and clinical expression of germ line predisposition to myeloid neoplasms in adults with marrow hypocellularity.Semantic proximity Read ↗

[Clinical significance of germline pathogenic variants associated with hematologic malignancies].Semantic proximity Read ↗

Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.Semantic proximity Read ↗

Genetic predisposition in acute leukaemia.Semantic proximity Read ↗

Germline Variants and Characteristic Features of Hereditary Hematological Malignancy SyndromeSemantic proximity Read ↗

Germline Variants and Characteristic Features of Hereditary Hematological Malignancy SyndromeSemantic proximity Read ↗

Prevalence and clinical implications of germline predisposition gene mutations in patients with acute myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.