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Article

Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.

Expert review of hematology - 1 Dec 2016

Duployez Nicolas, Lejeune Sophie, Renneville Aline, Preudhomme Claude

Abstract excerpt

INTRODUCTION: The determination of an underlying genetic predisposition is not automatically part of the diagnosis of hematological malignancies (HM) in routine practice. However, it is assumed that genetic predispositions to HM are currently underestimated due to great variations in disease phenotype, variable latency and incomplete penetrance. Most of patients do not display any biological or clinical signs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27819178
DOI: 10.1080/17474086.2016.1257936

Genes

DDX41
ETV6
GATA2
GSKIP
PAX5
RUNX1
SRP72
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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