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Article

Precision oncology revolution: CRISPR-Cas9 and PROTAC technologies unleashed

31 Jul 2024

Abstract excerpt

Cancer continues to present a substantial global health challenge, with its incidence and mortality rates persistently reflecting its significant impact. The emergence of precision oncology has provided a breakthrough in targeting oncogenic drivers previously deemed “undruggable” by conventional therapeutics and by limiting off-target cytotoxicity. Two groundbreaking technologies that have revolutionized the...

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CAR-T cell therapy research
CRISPR and Genetic Engineering
Protein Degradation and Inhibitors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39144725
DOI: 10.3389/fgene.2024.1434002

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