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Microbial cell-free DNA-sequencing as an addition to conventional diagnostics in neonatal sepsis

14 Aug 2024

Abstract excerpt

BACKGROUND: Bloodstream infections remain a challenge for neonatologists, as traditional culture-based methods are time-consuming and rely on adequate blood volume. Next-generation sequencing (NGS) offers an alternative, as it can identify microbial cell-free DNA (mcfDNA) in a small blood sample, providing rapid pathogen detection. This study aimed to assess the diagnostic performance of DISQVER®-NGS compared to...

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Share to Bacterial Identification and Susceptibility Testing
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PMID: 39143203
DOI: 10.1038/s41390-024-03448-1

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