Protective action of ascorbic acid against mutagenicity of aminopyrine plus nitrite.

Article

Protective action of ascorbic acid against mutagenicity of aminopyrine plus nitrite.

Polish journal of pharmacology and pharmacy - 1 Jan 2000

Pieńkowska K, Gajcy H, Koziorowska J

Abstract excerpt

Mutagenicity of aminopyrine and of aminopyrine plus nitrite was tested by the micronucleus test in bone marrow of mice and by host mediated mutagenicity assay with mice as host animals and S. typhimurium strain G 46. In parallel the possibility of the protective action of ascorbic acid was studie...

Topics

Aminopyrine
Animals
Ascorbic Acid
Bone Marrow
Female
Male
Mice
Mutagenicity Tests
Mutation
Nitrites
Nitroso Compounds
Salmonella typhimurium

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