Article
Integrative Multiomic Profiling of Triple-Negative Breast Cancer for Identifying Suitable Therapies.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2024
Jovanović Bojana, Church Sarah E, Gorman Kara M, North Khrystyna, Richardson Edward T, DiLullo Molly, Attaya Victoria, Kasparian Julie, Mohammed-Abreu Ayesha, Kirkner Gregory, Hughes Melissa E, Lin Nancy U, Mittendorf Elizabeth A, Schnitt Stuart J, Tolaney Sara M, Goel Shom
Abstract excerpt
PURPOSE: Triple-negative breast cancer (TNBC) is a heterogeneous disease that carries the poorest prognosis of all breast cancers. Although novel TNBC therapies in development are frequently targeted toward tumors carrying a specific genomic, transcriptomic, or protein biomarker, it is poorly understood how these biomarkers are correlated. EXPERIMENTAL DESIGN: To better understand the molecular features of TNBC...
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