Article
An artificially evolved gene for herbicide-resistant rice breeding.
Proceedings of the National Academy of Sciences of the United States of America - 20 Aug 2024
Dong Jin, Yu Xin-He, Dong Jiangqing, Wang Gao-Hua, Wang Xin-Long, Wang Da-Wei, Yan Yao-Chao, Xiao Han, Ye Bao-Qin, Lin Hong-Yan, Yang Guang-Fu
Abstract excerpt
Discovering and engineering herbicide-resistant genes is a crucial challenge in crop breeding. This study focuses on the 4-hydroxyphenylpyruvate dioxygenase Inhibitor Sensitive 1-Like (HSL) protein, prevalent in higher plants and exhibiting weak catalytic activity against many β-triketone herbicides (β-THs). The crystal structures of maize HSL1A complexed with β-THs were elucidated, identifying four essential...
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