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The Microbiome in Quiescent Crohn’s Disease With Persistent Symptoms Show Disruptions in Microbial Sulfur and Tryptophan Pathways

22 Nov 2023

Abstract excerpt

Background and Aims Even in the absence of inflammation, persistent symptoms in Crohn's disease (CD) are prevalent and worsen quality of life. Amongst patients without inflammation (quiescent CD), we hypothesized that microbial community structure and function, including tryptophan metabolism, would differ between patients with persistent symptoms ( qCD + S ) and without persistent symptoms ( qCD-S ). Methods We...

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PMID: 39129952
DOI: 10.1016/j.gastha.2023.11.005

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