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Article

Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype.

International journal of molecular sciences - 10 Apr 2023

Rojo-Tolosa Susana, Sánchez-Martínez José Antonio, Pineda-Lancheros Laura Elena, Gálvez-Navas José María, González-Gutiérrez María Victoria, Jiménez-Gálvez Gonzalo, Pérez-Ramírez Cristina, Morales-García Concepción, Jiménez-Morales Alberto

Abstract excerpt

Omalizumab is a monoclonal antibody indicated for the treatment of severe uncontrolled asthma with an allergic phenotype. Its effectiveness could be influenced by clinical variables and single nucleotide polymorphisms (SNPs) in one or more of the genes involved in the mechanism of action and process of response to omalizumab, and these could be used as predictive biomarkers of response. We conducted an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37108192
DOI: 10.3390/ijms24087029
PMCID: PMC10139019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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