Article
Haemophilus influenzae: using comparative genomics to accurately identify a highly recombinogenic human pathogen.
BMC genomics - 27 Aug 2015
Price Erin P, Sarovich Derek S, Nosworthy Elizabeth, Beissbarth Jemima, Marsh Robyn L, Pickering Janessa, Kirkham Lea-Ann S, Keil Anthony D, Chang Anne B, Smith-Vaughan Heidi C
Abstract excerpt
BACKGROUND: Haemophilus influenzae is an opportunistic bacterial pathogen that exclusively colonises humans and is associated with both acute and chronic disease. Despite its clinical significance, accurate identification of H. influenzae is a non-trivial endeavour. H. haemolyticus can be misidentified as H. influenzae from clinical specimens using selective culturing methods, reflecting both the shared...
Topics
- Cluster Analysis
- Genome, Bacterial
- Genomics
- Haemophilus influenzae
- Humans
- Phylogeny
- Polymorphism, Single Nucleotide
- Recombination, Genetic
- Sequence Analysis, DNA