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Article

Electroacupuncture at Zusanli regulates the pathological phenotype of inflammatory bowel disease by modulating the NLRP3 inflammasome pathway.

Immunity, inflammation and disease - 1 Aug 2024

Chen Yanqiang, Cai Miaomiao, Shen Boyuan, Fan Changchang, Zhou Xiang

Abstract excerpt

BACKGROUND: This study sought to explore the effect of electroacupuncture (EA) intervention at Zusanli (ST36) acupoint on modulating the NLRP3 inflammasome pathway for treating inflammatory bowel disease (IBD). METHODS: C57BL/6 mice were administrated with 3% dextran sulfate sodium (DSS) to construct the IBD model. DSS mice were then administrated with EA (10 Hz, 1.5 mA) at ST36 for 7 days or intragastric...

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Identifiers

PMID: 39119947
DOI: 10.1002/iid3.1366
PMCID: PMC11310853

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