Article
Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT.
Cell reports. Medicine - 20 Aug 2024
Hengist Aaron, Davies Russell G, Walhin Jean-Philippe, Buniam Jariya, Merrell Lucy H, Rogers Lucy, Bradshaw Louise, Moreno-Cabañas Alfonso, Rogers Peter J, Brunstrom Jeff M, Hodson Leanne, van Loon Luc J C, Barton Wiley, O'Donovan Ciara, Crispie Fiona, O'Sullivan Orla, Cotter Paul D, Proctor Kathryn, Betts James A, Koumanov Françoise, Thompson Dylan, Gonzalez Javier T
Abstract excerpt
Restricted sugar and ketogenic diets can alter energy balance/metabolism, but decreased energy intake may be compensated by reduced expenditure. In healthy adults, randomization to restricting free sugars or overall carbohydrates (ketogenic diet) for 12 weeks reduces fat mass without changing energy expenditure versus control. Free-sugar restriction minimally affects metabolism or gut microbiome but decreases...
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