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Article

Causal effect of COVID-19 on optic nerve and visual pathway disorders: genetic evidence of lung-brain axis.

Frontiers in immunology - 1 Jan 2024

Cao Chunge, Li Qiong, Cai Dajun, Yue Chaoyan, Zhao Hu

Abstract excerpt

Purpose: To investigate the potential causal association between COVID-19 exposure and optic nerve and visual pathway disorders through a two-sample bidirectional Mendelian randomization (MR) analysis, and to provide empirical support for the lung-brain axis. Methods: This MR analysis utilized publicly accessible summary-level data from genome-wide association studies on COVID-19 (n=158,783) and optic nerve and...

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Identifiers

PMID: 39081310
DOI: 10.3389/fimmu.2024.1440262
PMCID: PMC11286426

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