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Article

The Next Frontier in Tuberculosis Investigation: Automated Whole Genome Sequencing for Mycobacterium tuberculosis Analysis.

International journal of molecular sciences - 19 Jul 2024

Ng Justin H J, Castro Lina, Gorzalski Andrew, Allred Adam, Siao Danielle, Wong Edwina, Lin Andrew, Shokralla Shadi, Pandori Mark, Masinde Godfred, Khaksar Ramin

Abstract excerpt

A fully automated bacteria whole genome sequencing (WGS) assay was evaluated to characterize Mycobacterium tuberculosis (MTB) and non-tuberculosis Mycobacterium (NTM) clinical isolates. The results generated were highly reproducible, with 100% concordance in species and sub-lineage classification and 92% concordance between antimicrobial resistance (AMR) genotypic and phenotypic profiles. Using extracted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39063151
DOI: 10.3390/ijms25147909
PMCID: PMC11276714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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