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TP53 p.R337H Germline Variant among Women at Risk of Hereditary Breast Cancer in a Public Health System of Midwest Brazil.

Genes - 16 Jul 2024

Corrêa Tatiana Strava, Asprino Paula Fontes, de Oliveira Eduarda Sabá Cordeiro, Leite Ana Carolina Rathsam, Weis Luiza, Achatz Maria Isabel, de Oliveira Claudiner Pereira, Sandoval Renata Lazari, Barroso-Sousa Romualdo

Abstract excerpt

Despite the high prevalence of TP53 pathogenic variants (PV) carriers in the South and Southeast regions of Brazil, germline genetic testing for hereditary breast cancer (HBC) is not available in the Brazilian public health system, and the prevalence of Li-Fraumeni syndrome (LFS) is not well established in other regions of Brazil. We assessed the occurrence of TP53 p.R337H carriers among women treated for breast...

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Identifiers

PMID: 39062707
DOI: 10.3390/genes15070928
PMCID: PMC11276326

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TP53 p.R337H Germline Variant among Women at Risk of Hereditary Breast Cancer in a Public Health System of Midwest Brazil.PMID 39062707Read ↗

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