Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Upregulation of Neuroinflammation-Associated Genes in the Brain of SARS-CoV-2-Infected Mice

22 Jun 2024

Abstract excerpt

Neurological manifestations are a significant complication of coronavirus disease 2019 (COVID-19), but the underlying mechanisms are yet to be understood. Recently, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced neuroinvasion and encephalitis were observed in K18-hACE2 mice, leading to mortality. Our goal in this study was to gain insights into the molecular pathogenesis of neurological...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to Inflammasome and immune disorders
Share to Long-Term Effects of COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39057755
DOI: 10.3390/pathogens13070528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Upregulation of Neuroinflammation-Associated Genes in the Brain of SARS-CoV-2-Infected MicePMID 39057755Read ↗

Neurobiological Alterations Induced by SARS-CoV-2: Insights from Variant-Specific Host Gene Expression Patterns in hACE2-Expressing MiceSemantic proximity Read ↗

Impact of age and sex on neuroinflammation following SARS-CoV-2 infection in a murine modelSemantic proximity Read ↗

SARS-CoV-2 infection increases the gene expression profile for Alzheimer’s disease riskSemantic proximity Read ↗

Mouse Adapted SARS-CoV-2 (MA10) Viral Infection Induces Neuroinflammation in Standard Laboratory MiceSemantic proximity Read ↗

The K18-hACE2 mouse model of SARS-CoV-2 infection to illustrate the role and response of the vasculature in neurotropic viral infectionSemantic proximity Read ↗

Prion Infection of Mouse Brain Reveals Multiple New Upregulated Genes Involved in Neuroinflammation or Signal TransductionSemantic proximity Read ↗

Comparison of the Pathogenicity of SARS-CoV-2 Delta and Omicron Variants by Analyzing the Expression Patterns of Immune Response Genes in K18-hACE2 Transgenic MiceSemantic proximity Read ↗

SARS-CoV-2 Nsp2 Contributes to Inflammation by Activating NF-κBSemantic proximity Read ↗

Identification of host genes leading to West Nile virus encephalitis in mice brain using RNA-seq analysisSemantic proximity Read ↗

Neuroinvasion and neurotropism by SARS-CoV-2 variants in the K18-hACE2 mouseSemantic proximity Read ↗

A Murine Model of Post-acute Neurological Sequelae Following SARS-CoV-2 Variant InfectionSemantic proximity Read ↗

The central nervous system’s proteogenomic and spatial imprint upon systemic viral infections with SARS-CoV-2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.